Is this your skin issue?

  • Are you Seeing Eye bags, dark circles, lines and puffiness under your eyes?
  • Are you noticing the drooping mouth, sagging cheeks, fine lines and frowns?
  • Is your skin texture, becoming rough on touch or your skin tone is just not as illuminating, radiant, firm and healthy, as it used to be in the early years?

If you are experiencing any of these skin concerns, then PRP would be your best buddy to help you regain what you lost from your beloved facial skin.

The Science behind Platelet Rich Plasma (PRP) for skin rejuvenation

As now already known Platelet Rich Plasma is a natural product produced from a patient's own body. The specialist draws a small amount of blood the patient's body and place it in a sterile tube that is reeled down in a centrifuge to isolate the different components of the blood. White and Red blood cells are separated from the platelets and the plasma (the clear fluid). This plasma now comprises of quite a higher than usual number of platelets and is called platelet rich plasma, or PRP.

How Platelets Rejuvenate Skin?

PRP Rejuvenation

Platelets are the cells in the blood that allows the skin tissue to heal and generate new cells. The Platelet Rich Plasma, injected into particular parts of the skin, act as a matrix that accelerates a patient's own collagen to grow, regenerates tissue, and thus performs as to naturally soften and firm the skin. In this way, Platelet Rich Plasma smoothes out wrinkles and develops feathery and glowing skin texture and tone.

PRP simply works on a straightforward strategy of utilizing a patient's own natural platelets to guide the body to produce new collagen for tighter, softer, smoother, healthy and well-toned skin. Utilized in multiple techniques, with or without skin fillers, the platelet concentrated solutions can be administered with injections or by executing an automated micro-needling procedure or as a topical application to resurfacing.

Platelet Rich Plasma Skin Rejuvenation method often uses skin fillers with PRP – which stands for Platelet Rich Plasma – to improvise facial shape, texture, volume and laxity. It is a very simple in-clinic non-surgical cosmetic treatment which utilizes a concentrated serum being processed from a patient's own blood in combination with dermal filler to enhance the optimality and longevity of those fillers or alone to build up the natural collagen growth process.

How PRP works for Skin Rejuvenation

A small vial of blood is withdrawn from a patient's arm – less than that usually taken for regular blood tests. The extracted blood is then kept in a vial and spun in a centrifuge to separate the red blood cells and plasma. The mechanism concentrates the platelet count to around 4X times the normal count. It is this PRP– often called as “liquid gold” – that is then initialized and introduced into the skin – or done topically in a surface regeneration operation.

The Key to Success - PRP for Skin Rejuvenation-Tricking the cells inside assuming there is injury
The serum is energized by the inclusion of a normal calcium chloride. The energized plasma serum acts in the same way as the body would react if there were an actual injury – healing plasma rich platelets hurriedly run in to form a rich fibrin mesh. This newly created fibrin mesh in retaliation calls out to natural healing cells, disseminating growth factors and accelerating the process of fibroblast generation (the cells that form collagen) to stimulate and heal.

The ultimate result

  • Smoother, firmer and healthier appearance
  • Thicker dermis that ultimately cause the wrinkles and scars to shrink or die out
  • Enhanced skin tone

PRP for Skin Rejuvenation / PRP Facial Options

What is the rationale behind the use of PRP therapy to improve facial appearance?

An unceasing trend over the past 15 years has been for the patients to wanting less-invasive aesthetic enhancement or facial rejuvenation procedures. PRP has been used by the ace dermatologists and cosmetic surgeons all over the world over the past several years now to effectively speed up facial skin correction, treating different types of hair loss, stimulating soft-tissue healing from sports injuries as well as to treat burn sufferers and patients with extreme ulcers. PRP is also used as a supplementary therapy for implantation in field of dentistry.

Selphyl is a patent system that can be used for preparation of platelet-rich plasma for the purpose of cosmetically treating the volume loss in the face, neck, shoulder hands, -- and also specifically the crepe skin under neck and the eyes -- as well as acne scarring, stretch marks , wrinkles, folds, and fine lines.

There are various options available to enhance the results of PRP for skin and facial rejuvenation which includes:

OPTION 1: PRP with Skin Fillers = most impressive improvement
A true face “lift” effect is significantly accomplished with a combination of skin fillers, layered with the Platelet Rich Plasma serum. The skin fillers give an immediate volume or filling correction and the PRP – injected above the filler – instantly sets in motion the skin regeneration process. Patients can see and feel the effects within minutes as their skin becomes tauter and smoother.

Skin Filler products that are simultaneously used with the PRP serum are Juvederm Ultra plus Radiesse, Restylane or Perlane. The conjunction of PRP with skin fillers not only helps to improve a patient's skin tone and texture, but prolongs the effective filler repair for 4 to 6 months longer than when fillers are used alone.

Prolonged time span of skin fillers (Used with underlying hyaluronic acid based dermal fillers such as Restylane, Juvderm, or Radiesse, the PRP serum extends and intensifies the filler correction with the requirement for less filler per sitting and a longer time duration.)

OPTION 1: PRP with Skin Fillers = most impressive improvement
People who do not wish or feel the need to take dermal fillers along can benefit from the Platelet Rich Plasma itself. The energized PRP serum prepared from a patient's own blood can be injected just beneath the skin surface to accelerate the body to create a small amount of its own ‘filler'. However, this will not match up to the same effective results as a patient would achieve from a gel like filler such as Juvederm, Restylane or Perlane, but will certainly still experience improved textural changes.

Areas best for PRP therapy without filler include

  • Complete Face (when no filler required)
  • Full Neck and neckline (particularly horizontal necklace lines)
  • Crow's Feet also known as character lines or laugh lines that are bundles of tiny wrinkles, fine lines or creases formed in the corner of the eyes.
  • Under eye creases and Fine Wrinkles
  • Acne Scars
  • Décolletage- the uppermost part of torso, including shoulder, cleavage line or lower neckline

Platelets play a crucial role in stopping bleeding and in correcting destroyed blood cells, blood vessels, skin cells and tissues in the body. Platelets also consist of compounds known as “growth factors" that activate, energize and revitalize cells in our body. Unlike skin fillers that incorporate multiple synthetic substances in their preparation, PRP only makes use of the patient's natural biology to deal with the skin imperfections and volume loss, stimulating the generation of new cells and collagen production.

This state-of-the-art skin rejuvenation is a rapid 20-minute procedure. After 9 centimeter cube of blood (about 1 vial) is taken from the patient, it is then spun down in a centrifuge for 6 minutes at a pre-conceived speed to retrieve the most viable platelets and fibrin. After centrifugation, the platelet and fibrin compounds of the blood (the top most layers) is derived and re-injected into the affected area. This is the actual mechanisms by which injections of platelet-Rich Plasma restore and resurface the facial appearance.

Option 3: PRP Therapy Used as Laser Resurfacing Enhancement= 3rd most impressive improvement
Fractional laser treatments are widely recognized for their capability to improve or set a new or refine texture for skin. Adding PRP takes laser resurfacing to an all new level of re-texturing skin by expediting healing and accelerating desired new collagen production. Following your Fraxel RePair or Fraxel Restore treatment, energized PRP serum is applied to the skin that is preferably geared to accept the cut/skin-healing platelet serum.

Combining PRP with Fractional Laser
In a clinical study, cited by the American Society of Dermatologic Surgery, 22 women participated, that combined Platelet Rich Plasma with Fractional Laser treatments to assess the impacts on rejuvenating and replenishing their skin. Out of 22, 11 patients had a topical application of Platelet Rich Plasma in combination with three Fractional laser treatments, while the other 11 just had three Fractional Laser treatments alone. The patients were examined both before they were treated and a month after their treatments. Several different kinds of analysis were exercised, including blind clinical examinations, patient expectation, patient's satisfaction and even diagnosis of the skin. The final results clearly revealed that skin rejuvenation was better with Platelet Rich Plasma, and patient satisfaction was relatively higher with PRP as with that of Fractional Laser alone.

Option 4: PRP Facial= 4th most impressive improvement
The PRP Facial comprises of PRP applied over to the skin that has been activated by an automatic micro-needle. This automatic micro-needling when performed enables little “cuts” or “wounds” in the skin, which accept the Platelet Rich Plasma serum and initiates the process of collagen formation along with the tissue generation from the growth factors present in the plasma serum.

Combining PRP with Micro needling for Even Better Results

A research study in the Journal of Cutaneous and Aesthetic Surgery established a comparison between the outcomes of two different combination procedures. The first combination coupled Platelet Rich Plasma with a treatment called Micro needling, which is collagen introduction therapy. This pairing up therapeutically treatment was compared to Micro needling coupled with Vitamin C. Both the treatments were performed on patients with acne scars.

Thirty patients aged between 18 to 34 years participated in the study conducted in 2013, and availed four treatments each, in an interim of four weeks between every treatment. The right side of each patient's face was treated with the PRP and micro needling combos while the left side of each of those patients's face was treated with the Vitamin C and micro needling combination. To be involved in the study, the acne scars had to be rated on the Goodman and Baron scale with a Grade II, III or IV. Digital pictures of both sides of each patient's face were photographed before the treatments initiated and after they were finished using the similar positions, background and lighting.

Using the Goodman and Baron scale, the scarring from acne was again graded after treatments. Both practitioners and patients rated the improvement and modification of the grade of the acne scars. All the outcomes were accounted into Microsoft Excel database and assessed using standard statistical strategies. Of the 30 patients, 23 patients were reported to reduce the scars by one or two grades by PRP and micro needling combo.

If you are not using PRP and Microneedling you are missing out

Most females who have used the combination of Platelet Rich Plasma and collagen have given the treatment satisfactory to excellent reviews. A qualified plastic surgeon by profession who inducts the treatment to her patients had got it done herself and hugely recommends it. Dr. Lisa Zdinak, senior skin and cosmetic surgeon at Precision Aesthetics, stated the plasma in the PRP naturally accelerates the patient's stem cells and “charge them up” causing them to creating more collagen, which is what stimulates the skin to become more youthful, firm, smooth and healthy. Zdinak also mentioned that the plasma consists of proteins and molecules that offer essential nutrients to the skin's cells, so it is the healthiest, safest and the most natural way to enhance the laxity, texture and tone of the skin and minimize the appearance of wrinkles, scars and fine lines other signs of aging. If paired with some additional collagen, which also acts natural to the body, it yields even more effective results.

Platelet-Rich Plasma Facelift treatment Effects Are Lasting

Women who have had the PRP's Facelift procedure documented that their faces look even better few months after they have had obtained the treatments. That is because the plasma accelerates the patient's skin's stem cells to create more collagen, develop new cells and typically replenish and rejuvenate their skin. The newly generated cell growth in the skin stimulated by the PRP takes several weeks to months, which is why it appears so much better and natural after more time passes. Botox and other collagen based filler treatments exhaust in a lesser span of time, but the Platelet Rich Plasma lasts longer and looks much better as long as 1.5 to 2 years. The Food and Drug Administration (FDA) U.S has also not levied and restrictions or regulations on the use of Platelet Rich Plasma treatment because it comes directly from the person's own body and is not a drug. The use of Platelet Rich Plasma with other materials and few systems that prepare the PRP for ultimate use have been FDA passed, so make definite the one your specialist recommends is one of FDA cleared only.

Regenerative Medicine: Why There is No Bad Side Effects using PRP

PRP typically accelerates new cell growth in a person's body wherever it is injected. It enables the patient's body to heal itself the natural way without incorporating risk bearing chemicals or foreign materials of any kind. The chances of getting an infection or allergic reaction from the treatment is almost zero because the plasma is a derivative of a patient's own body.

Scientific Proof

The National Institutes of Health (NIH) has columned some reports from peer-reviewed medical journals on studies of the Platelet-Rich Plasma Facelift and wrinkle reduction treatment.AAD is also suggesting that PRP is good for face rejuvenation & wrinkle treatment.

One such research study, published by the Journal of Drugs in Dermatology in its May, 2010 issue, held over a 3 month period. The study has been conducted with 23 patients who were treated once every month. The blend of Platelet Rich Plasma mixed with an activating agent was injected into the targeted injection points on the face and neck area.

The participants involved in the study were imaged in both before and after their treatments with a digital camera and a medical photography instrument, called as a dermoscope. One month after the completion of the final PRP procedure, the patients returned back for a final assessment. Based on all the grades and markings of various aspects of an ideal correction in the skin, the study drawn the inference that outcomes were satisfactory, the treatment optimal and that the patients who participated counter no severe or incessant side effects. There are many more other studies also that credited the efficacy, safety and positivity of PRP for skin rejuvenation and face lift. The larger part of the women who reviewed their own PRP Facelift say they are totally satisfied with their results. Majority of women allows shared their experiences of cosmetic surgery and cited positive responses.

Precautions to be taken

Most skin specialists who administer Platelet Rich Plasma procedure ice their patients' faces instantly following the treatment to alleviate the temporary bruising that can take place in the target injection points. Icing the face will also help reduce any skin irritation or swelling for patients who have sensitive skin. All of these effects are temporary and are almost always disappear within some days itself.

Patients with sensitive skin may require taking extra precautions advised by their specialists. Provide adequate intervals between the sessions so that the skin has sufficient time to heal itself. Sensitive skin patients are not too prone to receive too many micro needling sessions too close together as it can cause skin infection and even swelling at the injection site.

The objective of Platelet Rich Plasma skin rejuvenation therapy is to enhance skin tone, tighten skin, soften wrinkles, fill in pores and improvise texture. Results start to be evident 3-4 weeks after the session and persist to improve with time. Three sessions of PRP procedure are generally recommended, spaced 1-2 months in between, to receive the best results.

PRP therapy can be effectively paired up with chemical peels, dermal fillers (Juvederm, Restylane, Perlane or Radiesse) laser treatments, Microdermabrasion, Dysport and/or Botox Cosmetic to excellently aim at a patient's distinctive skin and hair concerns and thus fulfill the final objective of younger and healthier looking skin. Post Maintenance PRP procedures should be given over time.